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LIVERWISE · Liver & MASLD

Healthy liver, healthy life.

Liver disease affects millions of people in the United States and Puerto Rico, and the vast majority are undiagnosed. The LIVERWISE: Healthy Liver, Healthy Life! project strengthens the science base to increase awareness of and prevent MASLD — Metabolic Dysfunction-Associated Steatotic Liver Disease — for all those affected.

50M

Americans affected by MASLD

90%+

Of those affected are undiagnosed

5–10%

Of all U.S. children have MASLD — more prevalent than asthma

Why It Matters

A condition most people never hear about.

Widespread, and hidden

Fifty million Americans are affected by MASLD, but more than 90% are undiagnosed.

Connected to other conditions

MASLD is closely linked to diabetes, cardiovascular disease, and excess weight, driving up the burden of chronic care management.

It reaches children

MASLD now affects 5 to 10% of all U.S. children, making it more prevalent than asthma. Hispanic children and teens with excess weight are at even higher risk.

The Program

First of its kind.

LIVERWISE expands and advances education, outreach, and public awareness related to liver disease, with a particular focus on MASLD, and supports effective, evidence-based and evidence-informed clinical and community-level interventions.

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The National Advisory Committee is co-chaired by Dr. Robert Lustig and Dr. Mauricio Lisker-Melman, and led by four regional coordinating site partners that provide community-informed guidance on program efforts to prevent, diagnose, and manage MASLD.

Boriken Neighborhood Health Center

Chicago Hispanic Health Coalition

Family Health Centers of San Diego

UTEP Center for Community Engagement

Resources

Know your liver.

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