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Liver • MASLD

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Liver disease affects millions of people in the United States and Puerto Rico, and the vast majority are undiagnosed. 

The LIVERWISE: Healthy Liver, Healthy Life! Project strengthens the science base to increase awareness of and prevent MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease) for all impacted by this condition.

  • 50 million Americans are affected by MASLD, but more than 90% are undiagnosed.  

  • MASLD is closely linked to diabetes, cardiovascular disease, and excess weight, driving up the burden of chronic care management.  

  • MASLD now affects 5-10% of all U.S. children, making it more prevalent than asthma. Hispanic children and teens with excess weight are at even higher risk.

LIVERWISE: Healthy Liver, Healthy Life!, is a first-of-its-kind program to expand and advance education, outreach, and public awareness related to liver disease, with a particular focus on MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease). LIVERWISE supports effective, evidence-based, and evidence-informed clinical and community-level interventions.

The National Advisory Committee is Co-Chaired by Dr. Robert Lustig and Dr. Mauricio Lisker-Melman and includes four regional coordinating centers (RCSs) that provide the essential community-informed review and guidance to prevent, support early diagnosis, and manage treatment of MASLD. The RCS’s are:​​

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